Profhilo is a widely requested skin treatment, and one that is often misunderstood. It is not a filler, and it does not change how your face moves. It works underneath the skin to improve hydration, firmness and overall skin quality. Knowing what it does, and what it doesn’t, is the best way to judge whether it suits your concern.
How Profhilo Actually Works

Profhilo is an injectable hyaluronic acid treatment, but unlike a dermal filler it isn’t designed to add volume or shape. It’s injected at a handful of points and spreads through the tissue, which is why it’s often called a skin quality treatment rather than a filler.
Straight after injection it draws in water and hydrates the skin from within. The manufacturer says it also supports the skin’s own collagen and elastin over the following weeks, which is why any change builds gradually rather than appearing all at once.
What Profhilo Doesn’t Do
Profhilo does not affect muscle movement, so it will not stop lines that appear when you frown, raise your eyebrows or squint. It does not add volume either, so it will not replace lost fullness in the cheeks or lips. Those are different problems. Movement lines are covered at a lines and wrinkles consultation, and lost volume is usually a conversation about dermal fillers.
Profhilo at a Glance
| What it treats | Skin hydration, firmness and overall quality |
| What it doesn’t treat | Lines caused by movement, lost volume, sagging |
| How it works | Hyaluronic acid that spreads through the skin and hydrates it |
| Typical areas | Face, neck, décolletage, hands |
| Course structure | Two sessions around four weeks apart |
| Maintenance | Roughly every six months |
| Regulatory status | CE-marked injectable, not a prescription-only medicine |
What Determines Profhilo Cost

Profhilo cost is driven mainly by the practitioner’s training and experience, followed by geography, with London clinics generally sitting above prices outside the capital. As general market context rather than a quote from Prof. Hindocha, five UK clinics publishing their own price lists put a single session between £220 and £380, checked October 2026.
| Clinic | Published Profhilo price |
|---|---|
| No.5 The Skin Clinic | £220 per session, two sessions for the initial course |
| The Aesthetics Suite | £299 per session |
| sk:n clinics | From £300 for one face treatment; £845 for a course of three |
| Laser Clinics UK | £325 for one treatment (2ml); £525 for a course of two (4ml) |
| Omniya, London | From £380 per session |
A two-session course comes to between £440 and £760 at those published per-session rates. The one clinic here publishing a two-session package, Laser Clinics UK, charges £525 for it.
A genuine figure for your own case can only come from an in-person consultation. Our broader guide to understanding the cost of private plastic surgery in the UK explains what a transparent quote should include.
What Real Profhilo Before and After Results Look Like
Honest expectations matter here. Profhilo before and after results are usually subtle: a more hydrated look with a gradual improvement in firmness, not a dramatic change, and not a substitute for treatments that address deeper lines or lost volume.
Because any effect builds over time, visible change typically develops over the weeks following the second session rather than appearing straight away. It’s most noticeable on the face, neck, décolletage and hands, areas prone to dehydration and fine crepiness.
We don’t publish Profhilo before-and-after photos, since results genuinely vary between patients and a stock gallery can be misleading. Our separate guide to Profhilo and skin boosters covers what to expect in more depth, and a consultation is the honest way to see how your own skin is likely to respond.
Who Profhilo Suits
If your skin looks dull, dehydrated or slightly crepey, particularly with no single line causing it, that’s a skin quality problem, and Profhilo is a reasonable starting point.
If the concern is lines that only show up when you frown or squint, or significant volume loss or sagging, Profhilo on its own is unlikely to be the answer. That’s a conversation for a lines and wrinkles consultation, dermal fillers or a surgical option instead.
Can Profhilo Be Combined With Other Treatments
Yes. It’s often used alongside dermal fillers, because the two target different things: Profhilo addresses skin quality, and filler addresses volume. Sequencing and spacing is a clinical decision best made at consultation, based on the areas being treated and your own skin.
Safety and Regulation in the UK
Any injectable treatment should be given by a registered healthcare professional after a proper assessment of your skin and medical history. It is worth checking your practitioner’s registration before you book.
Profhilo is a CE-marked injectable rather than a prescription-only medicine, but that doesn’t make technique any less important. A well-placed injection at the correct depth and points is what determines a safe, natural-looking result.
Profhilo With Prof Hindocha

Prof. Hindocha is a GMC-registered plastic surgeon and a member of both BAAPS and BAPRAS, offering Profhilo as part of a wider non-surgical practice. Rather than defaulting to whichever treatment is requested, each consultation starts with what your skin actually needs.
Frequently Asked Questions
Is Profhilo a filler?
No. Profhilo is a hyaluronic acid injectable, but it spreads through the skin rather than staying in one place to add volume. It is used for skin quality, not shape.
How much does Profhilo cost in the UK?
As general market context, five UK clinics publishing their own prices put a single session between £220 and £380, checked October 2026, and a two-session course between £440 and £760. Practitioner experience and location are the main factors, so a genuine figure needs an in-person consultation.
Can I have Profhilo with other treatments?
Yes. It is often combined with dermal fillers, since the two address different concerns. Your clinician will advise on sequencing and spacing based on the areas being treated.
How long do Profhilo results last?
Any change builds over the weeks after a two-session course and is generally maintained with a top-up roughly every six months, though this varies from person to person.
Does Profhilo help with frown lines?
Not directly. Profhilo does not affect muscle movement, so lines that appear when you frown or squint are a different problem. A consultation can confirm what is causing your lines.
Who is Profhilo best suited to?
People whose main concern is dull, dehydrated or crepey skin on the face, neck, décolletage or hands, rather than a specific line or lost volume.
Whether Profhilo is right for you depends on your own skin and goals. Book a consultation with Prof. Hindocha to get a personalised recommendation.
This article is for general information only and does not constitute medical advice. Individual results vary, and suitability for any treatment can only be confirmed following an in-person consultation with a qualified, registered clinician.


